2025-11-202025-11-202023Urueña A, Machado R, Cunha J, López Colmano C, Rancaño C, Kfouri R, Pírez C, Bonvehí P, Calvo M, Cuadros R, et al. Opinions, Attitudes and Factors Related to SARS-CoV-2 Vaccine Uptake in Eight South American Countries. Vaccines. 2023; 11(11):1660. https://doi.org/10.3390/vaccines111116602076-393Xhttps://doi.org/10.3390/vaccines11111660https://www.mdpi.com/2076-393X/11/11/1660/pdf?version=1698827240http://rid.isalud.edu.ar/handle/1/2981Fil: Urueña, Analia. Centro de Estudios para la Prevención y Control de Enfermedades Transmisibles CEPYCET, Universidad ISALUD.This article presents attitudes and practices regarding COVID-19 vaccination in the South American population. The study collected data from a self-administered survey distributed through social media platforms between February and April 2022 (N = 6555). The survey included questions related to participants’ sociodemographic background, flu vaccination practices, sources of information about COVID-19, and opinions regarding pandemic management and vaccination against SARS-CoV-2. The respondents agreed with the statement that COVID-19 vaccines were necessary (86.4%), effective (79.8%), safe (79.1%), and should be mandatory (64%). Overall, 83.4% accepted vaccination and 12.3% refused it completely. Main rejection reasons were safety (65.8%) and efficacy (54.9%) issues, and rushed development and approvals (49.1%). Vaccine uptake was associated with being ≥60 years, being a healthcare worker, previous influenza vaccine uptake, adherence to preventive measures, the death of ≥1 close people from COVID-19, and being informed through mass media or health authorities’ channels. Vaccine uptake inversely correlated with male gender, low educational level, and use of closed social networks for COVID-19 information purposes. This study provides valuable insights into COVID-19 vaccination attitudes and practices in South America that may be used to promote vaccine uptake in the region. Higher COVID-19 vaccination acceptance among people with previously acquired prevention habits reinforces the importance of routine health promotion strategies.enCC BY-NC-ND 4.0VACCINECOVID-19CORONAVIRUSVACCINATION HESITANCYVACUNASCOVID-19CORONAVIRUSRETICENCIA A LA VACUNACIÓNArtículo